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Antimony Sodium Tartrate
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C8H4Na2O12Sb2 581.61

Antimonate(2-), bis[µ-[2,3-dihydroxybutanedioato(4-)-O1,O2:O3,O4]]di-, disodium, stereoisomer.
Disodium bis[µ-[L-(+)-tartrato(4-)]]diantimonate(2-) [34521-09-0].
» Antimony Sodium Tartrate contains not less than 98.0 percent and not more than 101.0 percent of C8H4Na2O12Sb2, calculated on the dried basis.
Packaging and storage— Preserve in well-closed containers.
Identification— It responds to the tests for Antimony 191, for Sodium 191, and for Tartrate 191.
Acidity or alkalinity— Dissolve 1.0 g in 50 mL of carbon dioxide-free water, and titrate with 0.010 N hydrochloric acid or 0.010 N sodium hydroxide to a pH of 4.5: not more than 2.0 mL is required.
Loss on drying 731 Dry it at 105 to constant weight: it loses not more than 6.0% of its weight.
Lead 251: not more than 0.002%.
Residual solvents 467: meets the requirements.
(Official January 1, 2007)
Assay— Dissolve about 500 mg of Antimony Sodium Tartrate, accurately weighed, in 50 mL of water, add 5 g of potassium sodium tartrate, 2 g of sodium borate, and 3 mL of starch TS, and immediately titrate with 0.1 N iodine VS to the production of a persistent blue color. Each mL of 0.1 N iodine is equivalent to 14.54 mg of C8H4Na2O12Sb2.
Auxiliary Information— Staff Liaison : Behnam Davani, Ph.D., MBA, Senior Scientist
Expert Committee : (MDAA05) Monograph Development-Antivirals and Antimicrobials
USP29–NF24 Page 185
Phone Number : 1-301-816-8394