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Coal Tar Topical Solution
» Prepare Coal Tar Topical Solution as follows.
Coal Tar 200 g
Polysorbate 80 50 g
Alcohol, a sufficient quantity,
to make
1000 mL
Mix the Coal Tar with 500 g of washed sand (see under Reagents in the section Reagents, Indicators, and Solutions), and add the Polysorbate 80 and 700 mL of Alcohol. Macerate the mixture for 7 days in a closed vessel with frequent agitation. Filter, and rinse the vessel and the filter with sufficient Alcohol to make the product measure 1000 mL.
Packaging and storage— Preserve in tight containers.
Alcohol content 611: between 81.0% and 86.0% of C2H5OH.
Residual solvents 467: meets the requirements.
(Official January 1, 2007)
Auxiliary Information— Staff Liaison : Feiwen Mao, M.S., Senior Scientific Associate
Expert Committee : (MDOOD05) Monograph Development-Ophthalmics Oncologics and Dermatologicals
USP29–NF24 Page 576
Phone Number : 1-301-816-8320